In 2025, Germany reported the highest number of prevalent obesity cases among EU4 and the UK, with approximately 18 million cases
It is FDA-approved for several conditions, including pediatric growth hormone deficiency, adult growth hormone deficiency, Turner syndrome, idiopathic short stature, AIDS-associated wasting, and short bowel syndrome, and is sold under brand names including Genotropin, Humatrope, Norditropin, Saizen, and Omnitrope
The medications themselves do not directly cause muscle loss the mechanism is indirect: appetite suppression reduces overall food intake, which lowers protein consumption, at the same time that caloric restriction elevates whole-body EAA requirements
employed the Veterans Affairs healthcare database, including patients with metabolic dysfunction-associated steatotic liver disease [55]