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Magnesium sulfate attenuates lethality and oxidative damage induced by different models of hypoxia in mice
Mechanistically, Iso reduced ROS and MDA levels, enhanced SOD and CAT activity, and suppressed the NOX4/ROS/NF-B pathway by promoting Nrf2 nuclear translocation (Dai et al., 2018)
HUBERMAN: So the point is that if you want a specific biological effect, maybe you want to repair a given injury, or you'd like to get more growth hormone in order, I don't know, to get leaner or to recover from exercise more quickly or to feel more vitality, yes, there are peptides that can impact those pathways, but always, always, always, if you take peptides, especially therapeutic peptides, designed to promote activity within a given pathway for a specific purpose, you are going to activate other pathways as well
Excess supplementation may alter detoxification pathways or electrolyte balance, potentially worsening organ stress if not medically supervised
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