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Structure's GLP-1 Pill Could Be Big, But Trial Results Will Confirm Shares of Structure Therapeutics (NASDAQ: GPCR) have far outperformed both of the companies above in the last year, rising by over 150% during that time as investors have grown enthusiastic about aleniglipron, the firm's GLP-1 agonist candidate

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This antitumor effect was associated with a shift toward an immunostimulatory tumor-associated macrophage (TAM) phenotype and an enhanced effector T cell response within the tumor microenvironment, mediated by activation of the type I Interferon pathway (238)