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& Wanders, R
Glutathione acts as the frontline defense for liver cells (hepatocytes) during Phase 1, donating electrons to neutralize these dangerous free radicals
In addition, GLP-1 expression was down-regulated in wild-type Lox5 cells knocked out by FNDC5, and the induced expressions of lipolysis and autophagy-related genes and proteins were also inhibited, such as ATGL, HSL, and hepatic lipase deficiency gene (LIPC), suggesting that GLP-1 expression is also regulated by FNDC5, and may also provide therapeutic targets for lipid metabolism-related diseases
The free carnitine is transported to the cytosol by the CAC, and it can be recycled by CPT 1
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