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Together, this systems-level perspective positions proteostasis resilience as a foundational paradigm for understanding disease vulnerability and designing precision proteostasis-based therapies

GLP-1 drugs mimic the natural hormone to help people suffering from obesity, type 2 diabetes, and other metabolic conditions

References: Bacher I et al (2009): Mecamylamine a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders

Interestingly, a few reports have shown that exogenous and endogenous GLP-2 is a potential cancer promoter in mice models, although reduced inflammation was also observed (94, 95)