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GHRP-type peptides (ipamorelin, GHRP-6, GHRP-2, hexarelin) act on GHS-R1a, while GHRH analogs (CJC-1295, sermorelin, tesamorelin) act on GHRH-R
In this review, for amyloid and tau pathologies, outcomes varied: polyphenolic extract from PEBG (500 or 2500 mg/kg, p.o., for 4 months) had no impact on proteins such as beta-secretase 1 and metalloproteinase domain 10 [21], while quercetin (80 mg/kg, p.o., for 21 days or 16 weeks) lowered cathepsin B and tau phosphorylation [35, 39]
doi:10.1111/j.1472-8206.2008.00638.x, PMID: 19207541 Kumar A, Garg R (2008) Kumar P (2008) Nitric oxide modulation mediates the protective effect of trazodone in a mouse model of chronic fatigue syndrome
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