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Nrf2 activation suppresses ROS in antigen-presenting dendritic cells enhancing their capacity to interact with and promote the transformation of nave CD8 T cells into cytotoxic T lymphocytes enabling cytotoxic T-cells to eliminate virally infected cells (Kesarwani et al., 2013
Different pathways can still interact, and direct safety data is missing
Then, we asked whether the higher PM targeting of Go-Nt 31 compared to Go-Nt 7 might also be the outcome of different zDHHC substrate specificities
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