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For example, if you have 2.5mg/mL concentration and want a 0.5mg dose: (0.5 2.5) 100 = 20 IU

It is class-wide counter-regulation: stopping removes the signal that was holding down a set-point the body still defends. The felt marker of the rebound is the return of food noise, which patients in the exit interviews reported as the first sign the loss was reversing. Metabolic loss tracks weight regain

Vukojevic et al., 2020

The Regain Problem: What the Research Shows The STEP 1 trial extension following semaglutide patients after treatment ended found that body weight and cardiometabolic variables returned toward baseline values within 65 weeks of stopping the medication