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(4) Centrifuge for 10 min (12000 rpm, 4C), aspirate 150 L of the supernatant with a syringe, filter it using a 0.22 m organic phase pinhole filter, transfer it to an LC injection vial and store it at -80C until LC-MS analysis

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These findings support the conclusion that retatrutide has clinically measurable activity in type 2 diabetes, but it remains unapproved and is not an established diabetes medicine

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