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Those are FDA-approved brand-name medications trademarked by Novo Nordisk and Eli Lilly and Company respectively
CNS actions GLP-1R signaling plays a critical role in the maintenance of glucose homeostasis as deletion of the GLP-1R in mice results in impaired glucose tolerance (Scrocchi et al., In addition to this direct control of beta cells, GLP-1R signaling plays a role in the control of glucose homeostasis by regulating the activity of neurons both in the peripheral and central nervous system
There is no withdrawal syndrome
However, its important to note that using Semaglutide GLP-1 for weight loss in individuals with a BMI below 27 is not currently supported by clinical data or FDA approval
