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A newer GLP-1 receptor agonist, tirzepatide, demonstrates weight loss as high as 20% change in body weight compared with 3% in the placebo group in a RCT
The FDA distinguishes the categories explicitly: a generic is approved under section 505(j) and must establish therapeutic equivalence to a brand-name drug, while a compounded drug is not FDA-approved and the agency does not verify its safety, effectiveness or quality before marketing
Constipation is listed among the common side effects of Wegovy
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