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It is also important to avoid scratching or rubbing the injection site, as this can cause skin irritation
doi:10.1006/nbdi.2000.0304 Inoki K, Kim J, Guan KL (2012) AMPK and mTOR in cellular energy homeostasis and drug targets
These schedules are not clinically proven
This study showed that despite some clinical activity (albeit limited) in breast cancer, further clinical development of MEDI4276 is challenged by an unfavorable PK profile (insufficient to overcome a potential antigen sink) and high toxicity
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