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A 2019 analysis from the Hispanic Community Health Study / Study of Latinos (HCHS/SOL, N=16,415) found that HOMA-IR values were significantly elevated even among participants with normal BMI, suggesting a metabolic phenotype that is partly independent of adiposity [6]
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What is more, mechanistic study indicated that p53 activation was involved in the inhibitory effect of SLC7A11 induced by FA administration, which could be suppressed by LA supplementation
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