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This injectable formulation allows for much higher plasma concentrations of vitamin C, bypassing the limitations of gastrointestinal absorption and providing rapid systemic availability

This combined approach can be especially helpful for patients trying to avoid surgery or recover from chronic injuries

In contrast to chronic treatment with intact hGH, chronic treatment with AOD9604 showed no adverse effect on insulin sensitivity of the animals, as demonstrated with euglycemic clamp techniques Another study published in 2001 found the same thing, yet the results were very different for lean rats versus obese rats: Both hGH and AOD significantly reduced body weight gain in obese mice

Study 5: Phase 2b clinical study, failure in obesity Citation: Metabolic Pharmaceuticals Phase 2b trial (2007), not fully published