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Results A total of 11 studies were included in this meta-analysis, including 6 studies on GLP-1 RA, 1 study on GLP-1 and GIP dual receptor agonists, 1 study on orlistat, 2 studies on phentermine-topiramate, and 1 study on naltrexone-bupropion (Additional file 1: Table S2) [22,23,24,25,26,27,28,29,30,31,32]
In an in vivo (live animal) study, it takes much longer for those molecular changes to translate into whole-body physiological effects.
Numerous studies have demonstrated that treatment with L-carnitine and betaine significantly suppresses MPO gene expression [64,65,66,67,68,69,70,71]
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