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Drug effects in lean mice Single peripheral bolus administration (10 nmol kg 1 ) of GLP-1GIP and GLP-1GIPLani both induced conditioned taste avoidance (CTA) in lean wild-type mice, with GLP-1GIPLani having a slightly greater effect compared with GLP-1GIP, and without inducing CTA in glutamatergic ( Vglut2-cre ) Glp1r -knockout mice ( Vglut2 is also known as Slc17a6
Whether they work, or are safe, remains to be seen
In the KEMU study cohort, Sucrosomial B12 achieved a peak circulatry B12 concentration of 454 3.9 pg/mL by day 5, compared to 274 11.1 pg/mL with conventional Mecogen SL B12
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