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However, this trial did not specifically assess muscle mass as a primary or secondary endpoint, and the extent of any changes in lean mass versus fat mass requires further investigation with dedicated body composition measures
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They have not been through the rigorous clinical trial process that injectable tirzepatide completed
This suggests that GLP-1R-Gs activation rescues insulin secretion inhibited by pasireotide through the activation of SSTRs-Gi in GLP-1R-MIN-6 cells (Fig
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