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372 PLGA-PEG nanoparticle-based systems efficiently deliver HECTD2 inhibitors or KEAP1 stabilizers to inhibit HECTD2-mediated KEAP1 degradation, restoring KEAP1/NRF2 balance, suppressing antioxidant responses, and reversing lenvatinib resistance in HCC

It often leads to sarcopenic obesity, where muscle is lost and fat accumulates, which can reduce function and potentially affect long-term outcomes

Even though oral doses are much higher, the amount that actually works in your body is far lower

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