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Appetite & satiety: Dual GLP-1 + amylin signalling is reported to reduce appetite and increase satiety in trial subjects
Vitamin D, primarily in its active form 1,25-dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ], exerts its biological effects through binding to the vitamin D receptor (VDR), which is expressed in various cell types, including endothelial cells and vascular smooth muscle cells [13, 14]
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LPS activates astrocytes, triggering a reactive response characterized by the release of pro-inflammatory cytokines (e.g., TNF, IL-1, IL-6) and inducing a metabolic shift from OXPHOS to glycolysis to meet the energy demands of inflammation, thereby amplifying neuroinflammation
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