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Moreover, either exendin (939) or GLP-1R siRNA could not eliminate the metformin-induced upregulation of p-PKA protein level in PA-treated endothelial cells (Supplemental Fig
GW0742 can attenuate the increase of PARP activity caused by SAO shock
Activation of incretin receptors may theoretically affect sympathetic tone, which could contribute to heart rate elevation, though this mechanism requires further study in humans
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