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This once-weekly injection mimics natural hormones that regulate appetite and insulin sensitivity, making it highly effective
The only clinically relevant difference between treatments was the higher frequency of gastrointestinal related adverse events with IcoSema versus icodec or semaglutide alone, which can be mitigated by appropriate dosing recommendations for IcoSema, as discussed above
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Patients start at 0.25 mg to allow the body to adjust, then increase every 4 weeks until they reach 2.4 mg
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