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Tirzepatide (Zepbound) starts at 2.5mg weekly, increasing by 2.5mg every four weeks up to a maximum of 15mg, which takes approximately 20 weeks to reach if tolerated on schedule
For patients with obesity or overweight, these high barriers are a real detriment to health
If you find yourself struggling during weeks 3-8 of discontinuation, pausing the taper and holding your current dose for 2-4 weeks is clinically reasonable
Clinical Trials Real-world data paints a different picture compared to the controlled environment of clinical trials
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