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The aesthetic tanning market misrepresents this distinction: Melanotan-1 creates a real photoprotective tan through eumelanin synthesis, but that tan offers the equivalent of SPF 24 at maximum density
Many users combine both approaches, injecting for overall support while applying topical formulations to particularly problematic loose skin areas
PMCID: PMC9486455
Based on this evidence, it is recommended that long-term pharmacological management prioritize the optimization of treatment timing, formulation of personalized dosing regimens, and implementation of systematic efficacy monitoring and adverse reaction assessment protocols, to maximize therapeutic benefits while minimizing potential risks
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