Among them, the most typical is the chemokine Leukotriene B4 (LTB4), the increased expression of which causes recruitment of neutrophils, ATMs, T cells, and B cells, which increase expression of pro-inflammatory cytokines, eventually leading to the development of eWAT inflammation and obesity (132) ( Figure 3 )
Iranian Journal of Basic Medical Sciences 25:1487 Anbazhagan AN, Thaqi M, Priyamvada S, Jayawardena D, Kumar A, Gujral T, Chatterjee I, Mugarza E, Saksena S, Onyuksel H (2017) GLP-1 nanomedicine alleviates gut inflammation
Signals rising focus on metabolic and lifestyle disease management
Relying on lifestyle changes such as nutrition, physical activity, accountability and regular medical guidance, becomes essential once the medication is no longer providing its benefits