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Macedo LT, Lima JP, dos Santos LV, Sasse AD
Using in vitro liver models, we showed that these thiomethyl metabolites are directly linked to the elimination of the hepatotoxic NAPQI metabolites since S-CH 3 -APAP-S and SO-CH 3 -APAP-S are formed at high levels after exposure to NAQPI-derived metabolites (glutathione, cysteine, and mercapturate conjugates) in both primary human hepatocytes and HRG cells
When comparing IV chelation vs oral chelation, its impossible to say if one is objectively better since people have different needs
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