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The guanidinoacetate released by the kidneys is methylated by guanidinoacetate N -methyltransferase, which is located predominantly in the liver, pancreas, and, to a much lesser extent, in the kidneys to produce creatine (Wu and Morris 1998)
For the particle morphology, a JEM-2100 transmission electron microscope (TEM) (Japan Electronics Co., Ltd., Osaka, Japan) provided a larger view
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