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The use of GLP-1RA is a new therapeutic strategy that addresses both metabolic and cognitive/neuropsychiatric aspects, which is fundamentally important for the treatment of comorbid diseases
That is specifically visceral fat, the dangerous deep abdominal fat that drives metabolic disease
However, its relative impact on overall intraepithelial cell levels of GSH, or activation of other proinflammatory mediators, is unclear and requires further study
Lipid metabolism changes The glucagon receptor also reduces lipogenesis, the process by which the body converts excess calories into new fat stores
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