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In vivo antitumor efficacy assessment When the tumor volumes reached approximately 100 mm, twenty female BALB/c nude mice bearing 143B tumors were randomly assigned into four groups
Repurpose of the antibiotic NFT as activator of Nrf2 could thus be a promising strategy for a transient and targeted activation of the endogenous antioxidant machinery
Repositioned drugs thus have the built-in advantages of safety and clearly defined dosing, which may expedite a drugs regulatory process [122]
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