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Commenting on the MHRA review, Riccardo De Giorgi, clinical lecturer in the department of psychiatry at University of Oxford, said: It is reassuring that the MHRA conclusions regarding the safety of GLP1-RAs in terms of suicidality and depression match those of other international regulatory agencies, such as the EMA and US Food and Drug Administration

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5 Preclinical and clinical evidence The modulation of microRNAs (miRNAs) by flavonoids within the context of cardiovascular disease (CVD) represents an emerging area of research, with growing evidence suggesting beneficial effects of flavonoids on cardiovascular health via miRNA regulation

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