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Key considerations for protein targets: Use ideal body weight (IBW) or adjusted body weight for calculations, not current weight in patients with obesity Distribute protein across meals rather than concentrating in one sitting Monitor for signs of inadequate intake: fatigue, weakness, hair loss, or poor wound healing Reassess needs every 36 months as weight changes Consult with a registered dietitian for personalized recommendations GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists exert their appetite-suppressing effects through multiple mechanisms
View image online ( Glucagon-like peptide-1 (GLP-1) receptor agonists and GLP-1 receptor/glucose-dependent insulinotropic polypeptide (GIP) receptor dual agonists bind to their respective receptors on pancreatic beta cells to stimulate glucose-induced insulin secretion
212,213 The pathophysiological mechanism of GLP-1 in metabolic diseases GLP-1 plays a crucial role in the pathophysiology of metabolic diseases, particularly in T2DM and obesity
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