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Nonetheless, the underlying reasons for the inconsistencies in the reported associations between T2DM and levels of plasma DPP-4 activity (lower, unaltered, higher) have not been adequately explained, although one study did suggest that it might be related to the populations studied, with changes only becoming evident once moderate or severe hyperglycaemia becomes established (68)

However, a somewhat similar study found a significant benefit

Zhang X, Fu M, Wang Y, Wu T (2025) Strategies for delivering drugs across the blood-brain barrier for the treatment of neurodegenerative diseases

By promoting tissue regeneration and reducing inflammation, BPC 157 can assist in improving the range of motion and reducing stiffness in the joints (Seifert et al., 2020)