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A plateau on a stable dose is an expected endpoint rather than proof that semaglutide has stopped working
Fatigue: Initial fatigue can occur as your body adjusts
It lists individual metabolic rate as a factor, noting a faster metabolism may shorten symptom duration while slower clearance can extend nausea and appetite loss beyond ten days
This effect extends to ligament and skin repair, where IGF-1 activation supports fibroblast proliferation and extracellular matrix remodeling processes essential for tissue resilience
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