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These results evoke the speculation that higher dTTP level in T315I-Bcr-Abl-32D cells might prevent DNA replication stress to affect JMF4073 sensitivity

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They seem to be well tolerated in patients with mild and moderate liver function impairment, though they should be cautiously administered in patients with advanced liver disease.77,78 SGLT2 inhibitors Selective renal sodium glucose co-transporter 2 (SGLT2) inhibitors improve glycemic control in an insulin-independent fashion through inhibition of glucose reuptake in the kidney.79 The most used drugs from this group are: dapagliflozin, canaglifozin and empaglifozin

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