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A randomized, double-blind trial published in the Journal of Wound Care examined 82 patients with diabetic foot ulcers treated with either GHK-Cu-containing hydrogel dressing (1% concentration) or placebo gel over 12 weeks

Unlike most peptides, which are rapidly degraded by stomach acid and digestive enzymes, BPC-157 is derived from a protein naturally present in human gastric juice and has demonstrated remarkable resistance to enzymatic hydrolysis in gastric conditions

Initial loading protocols often use daily or every-other-day dosing for the first one to two weeks, followed by weekly, then monthly maintenance

Presented for research literature review only Cao K et al