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A 2006 Achilles-detachment study by Krivic and colleagues in the same journal applied BPC-157 intraperitoneally once daily at 10 g/kg, 10 ng/kg, or 10 pg/kg for 30 days in rats and reported that tendon-to-bone tissue, which did not heal spontaneously in saline controls, recovered with BPC-157 treatment, with directionally improved load-to-failure, stiffness, Young's modulus, and collagen organization at days 121, including in animals where healing had been impaired by 1 mg/kg 6-methylprednisolone though the abstract does not report numeric effect sizes or p-values
Variants IGF-1 variants are split into two groups: IGF-1 LR3 and DES IGF-1 (usually presented as IGF-1 DES)
Additives and excipients warrant attention
For example, spacing out moderate amounts of coffee throughout the day or avoiding coffee on an empty stomach may help
