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Compounding still constitutes unapproved new drug manufacturing under the FD&C Act, the floor that applies to all non-monograph peptides
Additional evaluations may include transcriptional and proteomic changes in metabolic signaling pathways, glucose transport assays (including markers associated with GLUT4 in adipocytes or skeletal muscle), and lipid-related metrics such as intracellular lipid accumulation or gene expression associated with lipogenesis
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