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This means addressing the triggers we discussed earlier: Manage Stress: Given that CRH directly activates mast cells, stress management isn't optional
The effect of IL-6 on the cartilage is similar to and in synergy with that of the other inflammatory cytokines and leads to a decrease in the synthesis of type II collagen and an increase in the matrix metalloprotease activity [5, 12]
Thus, it could be that GSH-cognition relationships only emerge in cases of more severe cognitive decline, when brain resources (such as antioxidant availability) have substantially declined
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