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A numerically lower MACE was observed with semaglutide, while tirzepatide demonstrated favorable heart failure profiles
Mitochondrial SIRT3, an NAD + -dependent deacetylase that modulates the stability of mitochondrial proteins, is diminished in the kidneys of mice exposed to cadmium, coinciding with reduced mitochondrial cristae levels, heightened GPX4 acetylation, and decreased mitochondrial GPX4 protein
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