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While the exact cause of rosacea is unclear, several factors are believed to contribute, including: Genetics: Rosacea tends to run in families

According to the Cleveland Clinic, it is usually seen in people who do not get enough vitamin B12 from their diet or when their digestive tract does not absorb enough

INCI: Water (and) Copper Tripeptide-1

COX-2 selective NSAIDs (i.e., COX-2 inhibitors or coxibs) inhibit COX-2 more strongly than COX-1, resulting in less gastrointestinal side effects, but potential cardiovascular complications, most notably an increase in the risk of heart attack due to increased blood clotting propensity (see below) (Conaghan 2012)