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Med Hypotheses (2019) 131:109308
While tirzepatide has yet to demonstrate direct cardiovascular risk outcomes in patients without type 2 diabetes, tirzepatide-treated groups did demonstrate reductions in cardiometabolic variables resulting in a significantly lower 10-year predicted ASCVD risk in patients with overweight or obesity without type 2 diabetes in post hoc analysis of the SURMOUNT-1 trial [49]
A common community model uses 300 mcg per day for four weeks, followed by 500 mcg per day for the rest of an 8- to 16-week timeline
Wen Q, Liu J, Kang R, Zhou B, Tang D
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