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Sean Wharton, an obesity doctor who has clinics in Ontario
Antibodies to type II collagen in early rheumatoid arthritis
Professor Jastreboffs research contributions include: Principal investigator for GLP3 phase 2 obesity trial demonstrating 24.2% weight loss Leadership in clinical research examining triple hormone receptor agonists Extensive investigations of incretin-based therapies for obesity and metabolic disease Pioneering work on combination approaches to weight management Studies examining neurobiological mechanisms underlying obesity pharmacotherapy Her work has helped establish GLP3 as one of the most promising next-generation obesity treatments in clinical development, contributing to the scientific foundation for multi-pathway metabolic interventions
Under research conditions, activation of GLP-1 and GIP receptors has been linked to modulation of glucose-dependent insulinotropic responses, regulation of glucagon secretion and effects on incretin signalling related to control of energy intake
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