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It has been shown that tretinoin (retinoic acid) and its derivatives, isotretinoin, adapalene and tazarotene, may decrease pigmentation in vitro most probably via the induction of keratinocyte proliferation and epidermal turnover acceleration, rather than by acting directly on melanogenesis [145]

There are several mechanisms by which glucagon prevents hypoglycemia, such as induction of hepatic gluconeogenesis and glycogenolysis, and the inhibition of hepatic glycogenesis

doi: 10.1111/liv.70210 133 ZhaoPPanBGaoJLvXWangYLiuJ