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Unlike peptide-based GLP-1 agonists, it does not require protection from digestive enzymes, enabling simple oral administration without fasting restrictions
MAPK, mitogen-activated protein kinase
These symptoms require urgent assessment to identify the underlying cause
Because of the GI effects, caution is advised in patients with severe gastroparesis (e.g., long-standing diabetic gastroparesis) GLP-1 RAs can worsen gastric emptying delays and are generally not recommended in that scenario
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