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The current development pipeline includes dual (e.g., tirzepatide [8], CagriSema [9]) and triple (e.g., retatrutide [10]) agonists with unprecedented efficacy in weight loss and glycemic control

If Medicare covered GLP-1s, the annual cost could be $13.6 billion (based on a 19% obesity rate from traditional Medicare diagnoses in 2021) to $26.8 billion (based on a 41.5% obesity rate from survey data for adults ages 60 and older)

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