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The immune system reacts faster, and symptoms can spike
Since SPRMs affect basic cell programming in hormone-sensitive tissues (not just the uterus) and are known to change endometrial architecture in novel ways, are they associated with an increased risk for cancer SPRMs are now being administered in Europe, so well be paying close attention to outcomes there
These associations were independent of factors including ethnicity, deprivation, microvascular complications, comorbidities, HbA1c, body mass index, and the use of other medications [23]
doi: 10.1016/j.chmed.2021.12.003
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