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240 In glioblastoma, hepatocyte growth factor (HGF)/c-Met signaling enhances -catenin nuclear localization and LEF1-dependent transcription of MDRassociated genes such as MRP-1, inducing CSC traits, endothelialmesenchymal transition (EndMT), and temozolomide resistance
L-arginine, the sole endogenous nitrogen donor for NOS, governs nitric oxide (NO) production during nervous system development and in various pathological conditions, including stroke, multiple sclerosis, PD and HIV-associated dementia
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