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The medication was approved by the FDA in 1959 for short-term usetypically 12 weeks or lessbecause its stimulant properties can lead to tolerance, dependence, and cardiovascular stress with prolonged use
doi:10.1016/j.rbmo.2009.06.005
Tirzepatide, the dual GIP/GLP-1 agonist, has shown even greater weight loss in head-to-head comparisons
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