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Dec 26, 2025 Some dermatologists say peptides and retinol work synergistically, but in the same time others warn about irritation or reduced effectiveness

Stimulation of the MEK5/Erk5 axis by IGF-IR bypasses the inhibition of BRAF, MEK1/2, and Erk1/2 [130]

GHK-Cu is the most clinically validated of the three, with human wound-healing and skin-regeneration data, and appears in approved cosmetic and dermatological products