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doi:10.1124/jpet.112.199497
A low acid content can also cause poor vitamin absorption
For instance, one mechanism involves promoting the production and secretion of GLP-1RAs, which significantly enhances glucose-induced insulin secretion by their interaction with specific receptors on pancreatic beta cells, which then simultaneously activates sensitive nerves and glucose receptors on beta cells to exert hypoglycemic effects ( In the event of acute infection, the pro-inflammatory factor IL-6 can induce the secretion of GLP-1 to optimize the level of blood sugar ( DPP-4 knockout, the administration of GLP-1 RAs can increase cardiac cAMP levels, improve cardiovascular function in animals with endotoxemia, and improve the prognosis of endotoxemia ( Effect of GLP-1RAs on Blood Glucose in Patients With Sepsis L-cells that secrete GLP-1 are a type of multifunctional endocrine cells that only exist in the intestinal mucosal epithelium
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