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Mielgo-Ayuso, L

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Nature 404 , 661671 (2000)

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Clinical Update 2/26/2026 Do Nitrate-Rich Vegetables Increase Cancer Risk

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MC1R is a G-protein-coupled receptor (GPCR) that, upon agonist engagement, activates the Gs/adenylate cyclase pathway, increasing intracellular cAMP and activating PKA-linked signalling cascades that upregulate tyrosinase activity and drive eumelanin synthesis the dark, UV-protective form of melanin

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